IIT Delhi Current Affairs

IIT Delhi researchers develops new nanotechnology-based drug delivery system

An all-women team of researchers from Indian Institute of Technology (IIT) Delhi has developed a new drug delivery platform using nanoparticles. 

The nanotechnology-based drug delivery system has ability to boost the efficacy of antibiotics at the cellular level and improve chances of recovery from cancer-related bacterial infections.

Need

In traditional drug delivery system, if the bacterial infection in cancer remains untreated, it can infect the host even after the cancer cells are killed by chemotherapy. Similarly antibiotics used in most conventional therapeutics has several issues such as improper biodistribution, lack of target specificity, poor water solubility and loss of efficacy over time due to the emergence of drug resistance in pathogenic bacteria. Moreover, 50% of these antibodies prescribed to humans are either not needed or not effectively utilised as prescribed.

Key Facts

In the nanotechnology-based drug delivery system, a peptide called sushi-peptide was conjugated [bound] to gold nanoparticles. It was found that this peptide bound to gold nanoparticles was able to kill E. coli and Salmonella typhi bacteria more efficiently at lower dosages at much lower concentration than free peptides. The nanoconjugate was able to kill 50% of bacteria at much lower concentration (400 nM) while the free peptide’s antibacterial activity was not significant at the same concentration.

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DRDO inks MoU with IIT Delhi to establish JATC

The Defence Research & Development Organisation (DRDO) has signed a MoU with Indian Institute of Technology (IIT) Delhi to establish a Joint Advanced Technology Centre (JATC).

The JATC will be located in the campus of IIT Delhi at the upcoming Science and Technology Park (Mini-Science Park ‘MSP’).

Key Facts

  • The objective of JATC is to undertake and facilitate multi-disciplinary directed basic and applied research in the jointly identified research verticals.
  • The JATC will enable Directed, Basic & Applied Research and will engage with premier research institutes through multi-institutional collaboration.
  • DRDO will support JATC in equipping it with advanced and unique research facilities to enable the faculty and scholars to conduct advanced research.
  • The researchers will get the opportunity to work in advanced areas of research such as Advanced Materials for Ballistic Protection, Advanced Electromagnetic Devices and Terahertz Technologies, Advanced Mathematical Modelling and Simulation, Smart & Intelligent Textile Technologies, Brain Computer Interface and Brain Machine Intelligence besides Photonic Technologies, Plasmonics and Quantum Photonics, etc.
  • It will facilitate towards advanced research to utilize technology outcome in the futuristic applications.
  • The focused research efforts at the JATC will help in realization of indigenous technologies the critical areas which will be used for speedy self-reliance.

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