Nanotechnology Current Affairs

IIT Delhi researchers develops new nanotechnology-based drug delivery system

An all-women team of researchers from Indian Institute of Technology (IIT) Delhi has developed a new drug delivery platform using nanoparticles. 

The nanotechnology-based drug delivery system has ability to boost the efficacy of antibiotics at the cellular level and improve chances of recovery from cancer-related bacterial infections.

Need

In traditional drug delivery system, if the bacterial infection in cancer remains untreated, it can infect the host even after the cancer cells are killed by chemotherapy. Similarly antibiotics used in most conventional therapeutics has several issues such as improper biodistribution, lack of target specificity, poor water solubility and loss of efficacy over time due to the emergence of drug resistance in pathogenic bacteria. Moreover, 50% of these antibodies prescribed to humans are either not needed or not effectively utilised as prescribed.

Key Facts

In the nanotechnology-based drug delivery system, a peptide called sushi-peptide was conjugated [bound] to gold nanoparticles. It was found that this peptide bound to gold nanoparticles was able to kill E. coli and Salmonella typhi bacteria more efficiently at lower dosages at much lower concentration than free peptides. The nanoconjugate was able to kill 50% of bacteria at much lower concentration (400 nM) while the free peptide’s antibacterial activity was not significant at the same concentration.

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Researchers develop first stretchable integrated circuit using an inkjet printer

Researchers from US based Michigan State University have developed the first stretchable integrated circuit (IC) made entirely using an inkjet printer.

This elastic material is made up of several materials fabricated from nanomaterials and organic compounds.  These compounds are dissolved in solution to produce different electronic inks, which can easily run through printer to make devices.

Key Facts
  • Using the ink, the researchers have successfully created the elastic material, the circuit and the organic light-emitting diode (OLED). The next step is combining the circuit and OLED into a single pixel.
  • Benefits: As the material is produced using a standard printer, it has a major potential cost advantage over current technologies that are expensive to manufacture.
  • Besides, stretchable electronic fabric can be easily folded and put in one’s pocket without breaking.
  • Potential applications: The new stretchable ICs can be used in smart tablet that could be stretched in size, from small to extra-large.
  • Besides, it can be used in wearable electronics like rubber band-like wrist monitor that measures the wearer’s heartbeat, soft robotics applications and wallpaper that turns an entire wall into an electronic display.

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