Council of Scientific and Industrial Research (CSIR) Current Affairs - 2020

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CSIR to develop new drugs for global market

The Council of Scientific and Industrial Research (CSIR) and Central Drug Research Institute (CDRI) signed an agreement to develop new drugs and repurposing of drugs for India and for global markets. The team research work is also joined by Cipla.

What is Drug Repurposing?

Drug repurposing is identifying new uses of approved or investigational drugs. It is used to treat common and rare diseases. The main advantage of using repurposing drugs is its reduced development cost, shortened development timings and increased use of de-risked compounds.

Cipla association with the institutes

The association of Cipla with the institutes has its origin in 1942. Cipla has also worked with the institutes in formulating the famous drugs called chandonium iodide in 1995. The drug is used against neuro muscular blockers. The drug was a huge hit in Indian and global markets. The gugulipid drug used for treating hypolipidemic was also developed under such venture.


The CSIR having a pan-India presence is known for its research and development in S&T areas. It includes oceanography, space physics, drugs, biotechnology, etc. CSIR is currently implementing a mission “New CSIR for New India” to be completed by 2022. The vision of the mission is to enable innovation-driven industry and catalyze inclusive economic development.

The institute holds 84th rank among 4851 institutions in the world according to the Scimago institutions ranking world report.

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CSIR Nuclear Magnetic Resonance Test gets US FDA certification

The CSIR-IICT, Hyderabad on December 3, 2019, announced that the US Food and Drug Administration (USFDA) cleared the Nuclear Magnetic Resonance (NMR) Test facility at the centre. The inspection was conducted between August 21, 2019 and August 22, 2019 with regard to Current Good Manufacturing Practices and was certified “No Action Initiated”.


The Research institute has largest facility of NMR laboratory in the country. It is equipped with nine NMR spectrometers. With the USFDA clearance the research center will gain further motivation to high quality research.

Why is USFDA clearance Essential?

The pharma and food products being exported to the US should adhere to CGMP (Current Goods Manufacturing Practices) according to FDA guidelines. On completion of inspection, FDA issues Form 483. The form includes warnings and corrective action plans if in need. Upon assertion from FDA, the product being manufactured through the certified process is allowed to be exported to the US.

NMR spectroscopy is important for structural characterization of chemical molecules used in pharmaceuticals. Bottom line, USFDA certification is essential and important to increase chemical and pharmaceutical exports to US.

US is the top export destinations of India’s Pharmaceuticals. In 2018-19, the Indian pharma exports to the US were 5820 million USD. Next to US, UK stands second with Indian pharma exports amounting to 630 million USD (2018-19), which is merely a tenth of exports to the US. Therefore, the USFDA certification is highly important to keep up the exports.

Nuclear Magnetic Resonance

Nuclear Magnetic Resonance is an analytical technique to determine the purity of a sample and its molecular structure. It is used to infer basic structure of unknown compounds. It helps to determine phase changes, solubility, conformational exchange and diffusion.

The technique is used to observe the local magnetic fields around atomic nuclei. Biochemists use NMR technique to identify proteins and other complex molecules.

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