Malaria Current Affairs - 2020

Four Mega Trials of COVID-19 Treatment launched by WHO

The World Health Organization recently launched a mega trial of four most promising corona virus treatments. The organization focuses on repurpose drugs that have already been approved to be safe rather than finding new compounds from the scratch.

What are the four trials?

The WHO is testing four most promising treatments to combat the virus. It includes

  • Remdesivir, an anti-viral compound
  • Chloroquine and Hydroxychloroquine, the Malarial medications
  • Combination of Lopinavir and Ritonavir, HIV drugs
  • Interferon-beta along with the combination of Lopinavir and Ritonavir


The drug was found to treat E-Bola viral infections. The E-bola outbreak broke out in Congo. The drug has been proved that it inhibits other Corona Virus Stains called SARS and MERS.

Chloroquine and HydroxyCholoroquine

This combination that is used to treat Malaria is another method that is being put under trial to treat Corona Virus. These drugs are being prescribed in India currently for the asymptomatic persons that come in direct contact with the persons infected with the virus.

Lopinavir and Ritonavir

The drugs were invented in the US in 2000. They have shown great efficacy in persons infected with MERS virus.

ICMR recommends Hydroxychloroquine to treat Corona Virus

The Indian Council of Medical Research had constituted a National Task Force to fight against COVID-19. The task force has recommended the use of Hydroxychloroquine to treat Corona Virus.


According to the task force, the Hydroxychloroquine can be used to treat asymptomatic health care workers. It shall be used to treat health care workers and household contacts of the patients who are asymptomatic.


The drug shall be provided to patients only through prescriptions. GoI recommends the use of Pharmacovigilance Programme of India app or helpline. The app allows self-reporting of the drug reactions. Also, while taking the drug, the asymptomatic contacts should maintain a self-quarantine.

Why Hydroxychloroquine?

The drug is usually prescribed to malaria patients. However, it is currently being used as an experimental treatment of COVID-19. Both South Korea and Italy have been using the drug to contain the spread of COVID-19. The US has also confirmed the efficiency of the in curing the disease in its early stages.